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Detection of the main periodontitis marker pathogens plus IL-1 and HLA-DR4 risk alleles

Simultaneous detection of periodontitis pathogens, IL-1 Genotype and HLA DR-4 risk allele

  • Test results available after approximately 4 hours
  • Control bands on each test strip confirm correct DNA isolation, amplification, and hybridization
  • Suitable for automated systems
  • Evaluation and documentation via the AID scanner and software
  • CE IVD

It has been proved by numerous scientific studies that a defined bacterial flora plays a part in the etiology of periodontal diseases and the failure of implants.

Some marker bacteria are thought to play a key role, because the exotoxins produced by these bacteria are directly connected with the continuance of the inflammation and the increasing loss of supporting tissue.

Inflammation promoting genotypes of cytokines (Il-1) and HLA predisposition HLA-DR4 amplify this effect. In order to introduce an antibiotic treatment of the bacteria which are often unavoidable during mechanical treatment, a microbiological diagnosis is necessary.

AID PeriodontitisPlus Kit enables a sensitive detection of periodontitis marker bacteria, determination of Il-1 Genotype and HLA-DR4 risk allele.

Characteristics

  • Detection of the 12 most important periodontitis marker pathogens, the most relevant risk alleles, and the HLA-DR4 allele from a single swab sample
  • Reverse hybridization kit (line probe assay) with preceding PCR
  • Specimen: subgingival plaque samples (swabs from periodontal pockets)
  • Article No. RDB 2040
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