PCR kit for genotyping the lactose intolerance allele

• Test results are available after approximately 4 hours
• Control bands on each test strip verify correct DNA isolation, amplification, and hybridization
• Suitable for automation
• Evaluation and documentation are performed using the AID scanner and software

• CE IVD

   

Lactose intolerance is the inability of some individuals to digest lactose, the sugar found in milk and dairy products. It is caused by reduced activity of the enzyme lactase-phlorizin hydrolase (LPH) in the small intestine, resulting in incomplete hydrolysis of lactose. In many cases, this is associated with genetic polymorphisms in a regulatory enhancer region upstream of the LCT gene. Undigested lactose is subsequently fermented by colonic bacteria, leading to symptoms such as abdominal bloating, cramps, flatulence, diarrhea, nausea, and vomiting.

The AID Lactose Intolerance Kit enables detection of the polymorphisms G/A −22018 and C/T −13910 in the regulatory enhancer region associated with lactase expression.