AID APO E APO B-100 PCR Kit – Detecting hyperlipoproteinemia risk alleles

• Test results available after approximately 4 hours
• Control bands on each test strip confirm correct DNA isolation, amplification, and hybridization
• Suitable for automated systems
• Evaluation and documentation via the AID scanner and software
• CE IVD

ApoE is a serum protein and is involved in the transport, storage and metabolism of cholesterol.

Hyperlipoproteinemia is mostly associated with risk allele ApoE-ε2. Studies show that 94,4% of patients are homozygous for ε2. On the other side only about 2% of people homozygous for ApoE-ε2 develop clinical phenotype of type III. Therefore further genetic or environmental factors must be involved in the development of the disease.

ApoB-100 is involved in metabolizing of cholesterol. Mutation Arg3500Gln of ApoB-100 gene results in reduced activity and a rise of cholesterol level in blood. This dysfunction in lipid metabolism results in a higher risk for hyperlipoproteinemia or arteriosclerosis.

AID Apo E + B Kit enables detection of risk alleles ApoE-ε2 and ApoB-100 Arg3500Gln.